Algae. 2004; 19(4): 349-352.
Screening for Aldose Reductase Inhibitory Activity of Extracts of the Marine Plants from Korea
Yeon Sil Lee, Sanghyun Lee1,*, Bak-Kwang Kim1 and Kuk Hyun Shin
Seokwon Life Science Research Institute, World Sea Green Co. Ltd., Paju 413-832, and 1College of Pharmacy, Seoul National University, Seoul 151-742, Korea
We examined MeOH extracts of the marine plants from Korea for their inhibitory activities on rat lens aldose reductase in vitro. Among the MeOH extracts tested, the extracts of Enteromorpha prolifera, Ecklonia cava, Pelvetia siliquosa and Salicornia herbacea exhibited a rat lens aldose reductase inhibition (IC: 3.04, 8.84, 11.42 and 4.99 g-ml, respectively) in vitro.
Keywords : aldose reductase activity; Ecklonia cava; Enteromorpha prolifera; Pelvetia iliquosa; Salicornia herbacea; marine plant